de Nijs J, Zoun K, Investigators G Psychiatr. Pol. 2014 Nov-Dec;48(6):1087-104 PMID: 25717480 Abstract AIM: Schizophrenia is a disorder with different outcomes. Besides the positive and negative symptoms, cognitive impairment is an important core feature of schizophrenia and often pre-dates the disorder. Cognition has consistently been related to outcome in schizophrenia. Given this finding and the fact that diagnosing and …
Evidence That Environmental and Genetic Risks for Psychotic Disorder May Operate by Impacting on Connections Between Core Symptoms of Perceptual Alteration and Delusional Ideation
Smeets F, Lataster T, Viechtbauer W, Delespaul P, Schizophr Bull 2014 Sep; PMID: 25217481 Abstract Background: Relational models of psychopathology propose that symptoms are dynamically connected and hypothesize that genetic and environmental influences moderate the strength of these symptom connections. Previous findings suggest that the interplay between hallucinations and delusions may play a crucial role in the development of psychotic …
Psychometric properties of the self-report version of the Quick Inventory of Depressive Symptoms (QIDS-SR16) questionnaire in patients with schizophrenia
Lako IM, Wigman JT, Klaassen RM, Slooff CJ, Taxis K, Bartels-Velthuis AA BMC Psychiatry 2014;14(1):247 PMID: 25178310 Abstract BACKGROUND: Self-report instruments for the assessment of depressive symptoms in patients with psychotic disorders are scarce. The Quick Inventory of Depressive Symptoms (QIDS-SR16) may be a useful self-report instrument, but has received little attention in this field. This paper aimed to test …
Factors contributing to the duration of untreated psychosis
Apeldoorn SY, Sterk B, van den Heuvel ER, Schoevers RA, Islam MA, , Schizophr. Res. 2014 Sep;158(1-3):76-81 PMID: 25043913 Abstract BACKGROUND: Shortening the duration of untreated psychosis (DUP) – with the aim of improving the prognosis of psychotic disorders – requires an understanding of the causes of treatment delay. Current findings concerning several candidate risk factors of a longer DUP …
Childhood abuse and neglect in relation to the presence and persistence of psychotic and depressive symptomatology
van Dam DS, van Nierop M, Viechtbauer W, Velthorst E, van Winkel R, , Bruggeman R, Cahn W, de Haan L, Kahn RS, Meijer CJ, Myin-Germeys I, van Os J, Wiersma D Psychol Med 2015 May;45(7):1363-77 PMID: 25065372 Abstract BACKGROUND: The association between childhood trauma and psychotic and depressive symptomatology is well established. However, less is known about the specificity …
Premorbid adjustment profiles in psychosis and the role of familial factors
Quee PJ, Meijer JH, Islam MA, Aleman A, Alizadeh BZ, Meijer CJ, van den Heuvel ER, J Abnorm Psychol 2014 Aug;123(3):578-87 PMID: 25000154 Abstract Disease heterogeneity in patients with psychotic disorder may be explained by distinct profiles of premorbid adjustment. The current study explored premorbid adjustment profiles in patients with psychotic disorders, associations with cognitive and clinical characteristics after disease …
Stereotype awareness, self-esteem and psychopathology in people with psychosis
van Zelst C, van Nierop M, Oorschot M, Myin-Germeys I, van Os J, Delespaul P, PLoS ONE 2014;9(2):e88586 PMID: 24523918 Abstract INTRODUCTION: Stigma is an important environmental risk factor for a variety of outcomes in schizophrenia. In order to understand and remediate its effects, research is required to assess how stigma experiences are processed at the level of the individual. …